Document 0053 DOCN M9490053 TI [Specificity of surface antigen and function of BAL T cells] DT 9411 AU Yamasaki H; Furuie H; Ando M; First Department of Internal Medicine, Kumamoto University School; of Medicine. SO Nippon Rinsho. 1994 Jun;52(6):1462-6. Unique Identifier : AIDSLINE MED/94322467 AB To elucidate the pathogenesis of sarcoidosis, we mainly investigated the surface molecules including adhesion molecules on BAL T cells and the functions of BAL T cells such cytokine production, [Ca2+] mobilization, PKC expression. Results are following. Adhesion molecules were up-regulated on BAL T cells compared with peripheral T cells, but cytokine production was decreased via TcR stimulation through [Ca2+] mobilization was occurred. PKC isozyme alpha expression was decreased compared with peripheral blood T cells. DE Antigens, Surface/*PHYSIOLOGY Bronchoalveolar Lavage Fluid/*CYTOLOGY Calcium/METABOLISM Cell Adhesion Molecules/METABOLISM Cytokines/METABOLISM CD4-CD8 Ratio English Abstract Human Protein Kinase C/METABOLISM Sarcoidosis/IMMUNOLOGY T-Lymphocytes/*IMMUNOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).